The core tenets of our research group are centred on the cognitive and neural functioning in mental impairments. Memory, attention and cognitive control constitute the key cognitive processes of interest in connection to anxiety, fear and other mental afflictions. On a neural level, we draw on structural and functional MRI techniques as well as quantitative EEG to investigate task- and rest-related brain activity. This includes novel neuroimaging technologies such as ultra-high field MRI at 7 Tesla, which permit probing the functioning of small nuclei in the brain. Using these tools, we explore alterations of the dynamic interaction between different neuronal networks and linking these back to the patients’ symptomatology. Insights gained from such task- and resting-state related changes in activation, connectivity, and complexity may provide more fine-grained neuronal markers, thus fostering better predictions of treatment outcomes compared to existing approaches in clinical practice.