Our team examines the neurobiological underpinnings of clinical high-risk (CHR) symptoms of psychosis and the consideration of developmental peculiarities in psychosis (risk) assessments. We examine the pathophysiological mechanisms of psychosis from risk stages to full-blown schizophrenia.
Further, we examine the psychophysiological and neurobiological alterations in adolescents with internet gaming disorder (IGD) in comparison to a healthy and a clinical control group.
We are especially interested in the interaction of the prefrontal cortex with deeper brain structures (e.g. the reward system, hippocampus) and its impact on neurocognition and psychopathology. Our goal is to improve early detection, increase knowledge of the pathophysiology and finally provide a basis for novel and personalized treatments for severe disorders that emerge in childhood or adolescence.