There appears to be great variability in the response to treatment among participants and the reason for this variability remains unclear. Given that interventions are resource intensive, the characterization and selection of those participants who might beneﬁt from treatment would greatly improve the practicability and effectiveness of those interventions. In this project, we seek to find variables that enable a prediction of treatment response. Possible prognostic variables might be the volume of certain brain areas, markers of plasticity, or physiological variables.
Peter J, Schumacher LV, Landerer V, Abdulkadir A, Kaller CP, Lahr J, Klöppel S.
Biological factors contributing to the response to cognitive training in mild cognitive impairment.
J Alzheimers Dis. 2018;61(1):333-345. doi: 10.3233/JAD-170580.